Registered Clinical Investigations
MMSx Authority conducts registered clinical investigations aligned with international ethical and research standards. All interventional studies are pre-registered on ClinicalTrials.gov prior to data collection, and conducted under GCP ICH E6(R3) and the Declaration of Helsinki (2013). Each record below links to its public ClinicalTrials.gov entry, where current recruitment status and the full protocol can be verified.
Study Registry — ClinicalTrials.gov
| Study | NCT Registration | Design | Planned n | Sites | Status |
|---|---|---|---|---|---|
| MOVE Protocol Movement-Oriented Velocity of Engagement |
NCT07220200 | Multi-site interventional case-series · 8-week · 4-phase | 40 | GFFI New Delhi · BodyGNTX USA · IIKBS | Registered · Results pending |
| BPIT Pilot Study 5-Line Principle — Strength, HRV & Injury Risk |
NCT07296640 | Prospective single-site · Paired t-tests α=0.05 · Cohen's d | 23 | BodyGNTX USA | Registered · Results pending |
| BPIT Multi-Site Study International Multi-Site Evaluation |
NCT07256717 | Multi-site single-arm interventional · 5 sites · Mixed-effects ANOVA | 369 | BodyGNTX · GFFI · IIKBS · AIHFT · BFS | Registered · Recruiting |
Pre-Specified Outcomes by Study
Pre-specified outcomes: pain indices, functional capacity, balance performance, and sit-to-stand metrics across sites in India and the USA. The full protocol is publicly available on ClinicalTrials.gov. Results to be reported on completion.
Pre-specified outcomes: strength, heart-rate variability, and knee-valgus loading, with a pre-registered statistical analysis plan. Framework archived on Zenodo (DOI 10.5281/zenodo.17594977). Results to be reported on completion.
Pre-specified outcomes: strength, heart-rate variability, and injury-mitigation measures across five international sites, designed to assess cross-site reproducibility. Protocol/preprint archived on Zenodo (DOI 10.5281/zenodo.17551763). Results to be reported on completion.
Ethics & Compliance
- GCP ICH E6(R3) — Good Clinical Practice guidelines for all registered investigations
- Declaration of Helsinki (2013 revision) — ethical principles for human subjects research
- Pre-registered Statistical Analysis Plans (SAPs) locked before data collection begins
- Independent statistician verification of primary analyses
- Open datasets archived on OSF and Zenodo (CC BY 4.0) for independent verification
- Conflict of interest disclosure on all publications